advanced rheology


  • Robust
  • Repeatable
  • Precise

Rouleaux formation is the first and most robust phase of RBC sedimentation after disaggregating (mixing) RBCs in whole blood samples. The classic Westergren method for measuring erythrocyte sedimentation rate (ESR) includes this phase, but relies upon time and gravity to “precipitate out” the resulting aggregated RBCs.

In the controlled environment of a micro-flow cell, the science of aggregation kinetics (rouleaux formation) is well defined and has a better than 95% correlation to the Westergren method, without the environmental variables that make Westergren and modified Westergen based methods difficult and time consuming to perform.

iSED’s advanced technology results in a test that takes only 20 seconds to complete and requires just 100uL of patient sample from a standard primary EDTA sample tube.